By Chi-Tang Ho, Toshihiko Osawa, Mou-Tuan Huang, Robert T. Rosen
content material: 1. vegetables and fruit --
2. Teas, spices, and herbs. v. 1. [no. 546] melanoma chemoprevention by means of phytochemicals in vegetables and fruit : an summary / Mou-Tuan Huang, Thomas Ferraro, and Chi-Tang Ho --
results of nutrients phytochemicals on xenobiotic metabolism and tumorigenesis / Theresa J. Smith and Chung S. Yang --
Micronutrients in melanoma prevention / Paul A. Lachance --
Antimutagen and anticarcinogen learn in Japan / Mitsuo Namiki --
Flavorants from garlic, onion, and different alliums and their cancer-preventive homes / Eric Block --
Inhibition of chemical toxicity and carcinogenesis by means of diallyl sulfide and diallyl sulfone / J-Y. Hong, M.C. Lin, Zhi Yuan Wang, E-J. Wang, and Chung S. Yang --
Breath research of garlic-borne phytochemicals in human topics : mixed adsorbent trapping and short-path thermal desorption gasoline chromatography-mass spectrometry / Reginald Ruiz, Thomas G. Hartman, Karl Karmas, Joseph Lech, and Robert T. Rosen --
Sulfur chemistry of onions and inhibitory components of the arachidonic acid cascade / Shunro Kawakishi and Y. Morimitsu --
Vinyldithiins in garlic and jap family Allium (A. victorialis) / H. Nishimura and T. Ariga --
Thermal decomposition of alliin, the foremost taste portion of garlic, in an aqueous resolution / Tung-Hsi Yu, Chi-Kuen Shu, and Chi-Tang Ho --
Chemoprotection by way of l,2-dithiole-3-thiones / T.W. Kensler, J.D. Groopman, B.D. Roebuck, and T.J. Curphey --
Chemoprevention of colon melanoma by way of thiol and different organosulfur compounds / Bandaru S. Reddy and Chinthalapally V. Rao --
Inhibition of esophageal tumorigenesis through phenethyl isothiocyanate / G.D. Stoner, A.J. Galati, C.J. Schmidt, and M.A. Morse --
High-performance liquid chromatographic choice of glucosinolates in brassica greens / J.M. Betz and W.D. Fox --
Biochemistry of citrus limonoids and their anticarcinogenic job / Shin Hasegawa, Masaki Miyake, and Yoshihiko Ozaki --
Inhibition of chemically prompted carcinogenesis by means of citrus limonoids / Luke K.T. Lam, Jilun Zhang, Shin Hasegawa, and Herman A.J. Schut --
Inhibition of oral carcinogenesis through eco-friendly espresso beans and limonoid glucosides / E.G. Miller, A.P. Gonzales-Sanders, A.M. Couvillon, J.M. Wright, Shin Hasegawa, Luke K.T. Lam, and G.I. Sunahara --
Stimulation of glutathione S-transferase and inhibition of carcinogenesis in mice via celery seed oil parts / G.-Q. Zheng, Jilun Zhang, P.M. Kenney, and Luke K.T. Lam --
Citrus juice flavonoids with anticarcinogenic and antitumor houses / John A. Attaway --
choice of loose and glycosidically certain natural compounds in an umbelliferous vegetable drink / Robert T. Rosen, Tarik H. Roshdy, Thomas G. Hartman, and Chi-Tang Ho --
results of intake of an umbelliferous vegetable beverage on ingredients in human sera / H.E. Sauberlich, D.S. Weinberg, L.E. Freeberg, W.-Y. Juan, T.R. Sullivan, T. Tamura, and C.B. Craig --
Chlorophyllin : an antigenotoxic agent / T. Ong, H.E. Brockman, and W-Z. Whong --
nutritional cytochrome P-450 modifiers within the keep an eye on of estrogen metabolism / Jon J. Michnovicz and H. Leon Bradlow --
Comparative learn of ellagic acid and its analogues as chemopreventive brokers opposed to lung tumorigenesis / Andre Castonguay, Mohamed Boukharta, and Guylaine Jalbert --
Antitumor-promoting results of gallotannins, ellagitannins, and flavonoids in mouse pores and skin in vivo / J.P. Perchellet, H.U. Gali, E.M. Perchellet, P.E. Laks, V. Bottari, R.W. Hemingway, and A. Scalbert --
Soybean saponin and isoflavonoids : constitution and antiviral task opposed to human immunodeficiency virus in vitro / Kazuyoshi Okubo, Shigemitsu Kudou, Teiji Uchida, Yumiko Yoshiki, Masaki Yoshikoshi, and Masahide Tonomura --
Structural elucidation and physiological homes of real soybean saponins / Shigemitsu Kudou, Masahide Tonomura, Chigen Tsukamoto, Teiji Uchida, Masaki Yoshikoshi, and Kazuyoshi Okubo --
Fermentation-derived anticarcinogenic taste compound / Michael W. Pariza --
Antioxidative job of fermented soybean items / H. Esaki, H. Onozaki, and Toshihiko Osawa --
Chemopreventive phytochemicals in soy and licorice diets affecting key rat enzyme platforms / T.E. Webb, %. Stromberg, H. Abou-Issa, M. Moeschberger, H.F. Pierson, and R.W. Curley, Jr. --
Genetic development of saponin elements in soybean / Chigen Tsukamoto, Akio Kikuchi, Shigemitsu Kudou, Kyuya Harada, Tsutomu Iwasaki, and Kazuyoshi Okubo --
the second one golden age of food : phytochemicals and ailment prevention / Mark Messina and Virginia Messina --
Synthesis of L-ascorbic acid and its 2-phosphate and 2-sulfate esters and its position within the browning of orange juice focus / Eldon C.H. Lee --
Metabolic pathway for [beta]-carotene biosynthesis : similarities within the plant and animal / A.M. Gawienowski. v. 2. [no. 547] Phytochemicals in teas and rosemary and their cancer-preventive houses / Chi-Tang Ho, Thomas Ferraro, Qinyun Chen, Robert T. Rosen, and Mou-Tuan Huang --
Inactivation of oxygen radicals via nutritional phenolic compounds in anticarcinogenesis / Michael G. Simic and Slobodan V. Jovanovic --
Prophylactic services of tea polyphenols / Yukihiko Hara --
Preventive impact of eco-friendly tea polyphenols on colon carcinogenesis / Mujo Kim, Nobuyuki Hagiwara, S.J. Smith, Takehiko Yamamoto, Tetsuro Yamane, and Toshio Takahashi --
Tea polyphenols as a singular category of inhibitors for human immunodeficiency virus opposite transcriptase / Hideo Nakane, Yukihiko Hara, and Katsuhiko Ono --
Mitogenic job of ( --
)-epigallocatechin gallate on B cells and its structure-function courting / Z.-Q. Hu, M. Toda, S. Okubo, and Tadakatsu Shimamura --
Suppression of the formation of complicated glycosylation items by way of tea extracts / N. Kinae, ok. Shimoi, S. Masumori, M. Harusawa, and M. Furugori --
results of tea polyphenols on blood rheology in rats fed a high-fat vitamin / F. Nanjo, Yukihiko Hara, and Y. Kikuchi --
Inhibition of saccharide digestive enzymes by means of tea polyphenols / M. Honda, F. Nanjo, and Yukihiko Hara --
Interactions of eco-friendly tea catechin with polyamides / H. Li, C. Fisher, R.W. Keown, and C.P. Malone --
Inhibition of influenza virus an infection by means of tea polyphenols / Tadakatsu Shimamura --
Inhibitory impact of rooibos tea (Aspalathus linearis) at the induction of chromosome aberrations in vivo and in vitro / okay. Shimoi, Y. Hokabe, Y.F. Sasaki, H. Yamada, okay. Kator, and N. Kinae --
Prevention of melanoma through brokers that suppress creation of oxidants / W. Troll, J.S. Lim, and okay. Frenkel --
melanoma chemoprevention via antioxidants / Masao Hirose, Katsumi Imaida, Seiko Tamano, and Nobuyuki Ito --
Chemistry and antioxidative results of phenolic compounds from licorice, tea, and composite and labiate herbs / Takuo Okuda, Takashi Yoshida, and Tsutomu Hatano --
Chemistry of antioxidants from Labiatae herbs / Nobuji Nakatani --
Flavonoid with powerful antioxidative job remoted from younger eco-friendly barley leaves / Takayuki Shibamoto, Yoshihide Hagiwara, Hideaki Hagiwara, and Toshihiko Osawa --
Antioxidative compounds from marine organisms / ok. Sakata, ok. Yamamoto, and N. Watanabe --
Chemistry and antioxidative mechanisms of [beta]-diketones / Toshihiko Osawa, Y. Sugiyama, M. Inayoshi, and Shunro Kawakishi --
Molecular mechanism of motion of curcumin : inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced responses linked to tumor promoting / J.K. Lin, T.S. Huang, C.A. Shih, and J.Y. Liu --
Formation and reactivity of loose radicals in curcuminoids : an electron paramagnetic resonance learn / K.M. Schaich, C. Fisher, and R. King --
anti inflammatory and cancer-preventive immunomodulation via nutrition : results of curcumin on T lymphocytes / Marion Man-Ying Chan and Dunne Fong --
research of curcuminoids by way of high-performance liquid chromatography / Thomas H. Cooper, Joseph G. Clark, and James A. Guzinski --
constitution of antioxidative compounds in ginger / Hiroe Kikuzaki, Yoko Kawasaki, and Nobuji Nakatani --
Chemistry of ginger elements and inhibitory components of the arachidonic acid cascade / Shunro Kawakishi, Y. Morimitsu, and Toshihiko Osawa --
Antitumor promoters from safe to eat vegetation / H. Ohigashi, A. Murakami, and okay. Koshimizu --
Chemistry of lignan antioxidants in sesame seed and oil / Y. Fukuda, Toshihiko Osawa, Shunro Kawakishi, and M. Namiki --
Chemistry and antioxidative task of lignan glucosides in sesame seed / Hirotaka Katsuzaki, Toshihiko Osawa, and Shunro Kawakishi --
Antioxidative and anticancer elements produced via mobile tradition of sesame / A. Mimura, okay. Takebayashi, M. Niwano, Y. Takahara, Toshihiko Osawa, and H. Tokuda --
improvement of stability-indicating analytical tools for flaxseed lignans and their precursors / R.K. Harris, J. Greaves, D. Alexander, T. Wilson, and W.J. Haggerty --
Antitumor-promoting and anti inflammatory actions of licorice rules and their changed compounds / Shoji Shibata --
organic actions, construction, and use of chemical elements of licorice / Kenji Mizutani --
Anticarcinogenesis of licorice and its significant triterpenoid materials / Zhi Yuan Wang --
Ginseng and its congeners : conventional Oriental foodstuff medicines / Osamu Tanaka --
average items and organic actions of the chinese language medicinal fungus Ganoderma lucidum / Ming-Shi Shiao, Kuan Rong Lee, Lee-Juian Lin, and Cheng-Teh Wang.
By Michael F. Holick (auth.), Dr. Jörg Reichrath, Prof.Dr. Wolfgang Tilgen, Dr. Michael Friedrich (eds.)This quantity presents a complete, hugely readable evaluation of the subjects mentioned on the First foreign Symposium on "Vitamin D Analogs in melanoma Prevention and treatment" held in Homburg/Saar, Germany in may perhaps 2002. prime researchers talk about our current wisdom of the nutrition D method in melanoma. issues diversity from the latest findings in molecular biology, epidemiology, synthesis and metabolism of nutrition D to new ideas for using diet D analogs in melanoma prophylaxis and remedy. The publication offers crucial up to date details for each researcher or clinician attracted to the biology of nutrition D or cancer.
By A. Fitoussi, M. G. Berry, B. Couturaud, R. J. Salmon
'Oncoplastic and Reconstructive surgical procedure for Breast melanoma describes the reconstructive suggestions which have been sophisticated over the last decade by way of surgeons in a truly excessive quantity unit. It offers transparent descriptions of the entire to be had recommendations. With confirmed event within the techniques defined and specified clinical evaluate, it additionally presents evidence-based literature reports.
The e-book begins with the proper anatomical historical past and passes via the entire significant oncoplastic and reconstructive strategies to be had to the breast melanoma sufferer. It contains administration of breast and nipple-areolar advanced reconstruction as well as symmetrising surgical procedure and the recent means of fats move. It additionally covers all multidisciplinary facets and genetics therefore giving an up to date prestige report.
By P. Fraser, A. M. Adelstein (auth.), Professor William Duncan (eds.)
Colorectal melanoma used to be the topic of the 3rd Symposium on medical Oncology equipped by way of the Royal collage of Radiolo gists, London, in February 1981. This book of gathered papers is predicated at the shows at that assembly. the aim of those symposia is to motivate a multidis ciplinary method of our figuring out and administration of melanoma. they convey jointly not just clinicians of other specialities, but in addition non-clinical scientists who even have made an important contribution either to simple wisdom and to functions of direct medical relevance. it's was hoping that sym posia of this sort should be a stimulus to expanding collaborative learn. Colorectal melanoma is now the most very important motives of melanoma deaths. The prevalence of the disorder varies enormously in the course of the international yet is especially universal in North the US, Canada, and Western Europe. The aetiology of colorectal melanoma is reviewed and a transparent description is given of the standards linked to its excessive prevalence in prosperous Western societies. there's nonetheless no facts of an instantaneous associa tion among nutritional ingredients and colorectal melanoma, and so adjustments in our nutritional behavior that will aid to minimize the occurrence of this sickness can't be suggested. whereas learn VI Preface during this vital box maintains, advancements needs to be sought in strategies of early prognosis, evaluate and management.
By Institute of Medicine and National Research Council
The nationwide melanoma coverage Board and the Board on technological know-how, Engineering, and financial coverage convened a workshop in January 2004 on "Economic types of Colorectal melanoma (CRC) Screening in Average-Risk Adults". the aim of the workshop was once to discover the explanations for changes between major cost-effectiveness research (CEA) versions of CRC screening, which public well-being coverage makers more and more depend upon to assist them sift during the many selections confronting them. individuals mentioned the result of a collaborative pre-workshop workout undertaken through 5 examine groups that experience constructed and maintained finished types of CRC screening in average-risk adults, to realize perception into each one model's constitution and assumptions and attainable causes for changes of their released analyses. The workshop members additionally tested the present nation of data on key inputs to the types with a view towards deciding on parts the place additional learn should be warranted. This record summarized the displays and dialogue on the workshop.
By Jiemin Ma, Ahmedin Jemal (auth.), Aamir Ahmad (eds.)
This quantity comprehensively covers contemporary prrogress in breast melanoma examine. for you to effectively deal with breast melanoma, it truly is central to a) absolutely comprehend the affliction with all its heterogeneity, b) comprehend the criteria that effect the metastasis of breast melanoma to far-off organs making it deadly and c) comprehend the underlying tactics that bring about the phenomenon of drug-resistance making the illness rather incurable. The booklet explores all of those matters, together with the phenomenon of epithelial-mesenchymal-transition, melanoma stem cells in addition to microRNAs in an try and greater comprehend the affliction in connection to its heterogeneity/metastasis/drug-resistance in addition to to suggest novel signaling pathways for healing intervention. The profiling of tumors to molecularly classify breast cancers can be investigated in order that custom-made detailed cures may be built.
By Jonathan Strauss, William Small, Gayle E. Woloschak
This is the 1st textbook of its sort dedicated to describing the organic complexities of breast melanoma in a manner that's suitable to the radiation oncologist. Radiation Oncology has lengthy handled breast melanoma as a unmarried organic entity, with all remedy judgements being according to scientific and pathologic chance components. we're now starting to remember that organic subtypes of breast melanoma can have diversified dangers of recurrence in addition to diverse intrinsic sensitivity to radiotherapy. Multi-gene arrays that experience for years been used to foretell the danger of far-off recurrence and the price of systemic chemotherapy can also have application in predicting the chance of neighborhood recurrence. also, the specified brokers used to regard breast melanoma might engage with radiotherapy in ways in which might be precious or bad. All of those rising matters are greatly mentioned during this e-book, and functional evidence-based therapy innovations are offered every time attainable.
By Sabrina McCormick
No family members heritage offers compelling facts of environmental hyperlinks to breast melanoma, starting from daily cosmetics to business waste. Sabrina McCormick weaves the tale of 1 survivor without family members historical past right into a robust exploration of the massive enterprise of breast melanoma. As medications, crimson items, and company sponsorships generate huge, immense profit to discover a therapy, an increasing number of specialists argue that we should always as an alternative raise specialise in prevention_reducing environmental exposures that experience contributed to the pointy elevate of breast melanoma charges.
By Christopher R. Cogle (auth.), Alison L. Allan (eds.)
The “cancer stem mobilephone” speculation postulates that melanoma arises from a subpopulation of tumor-initiating cells or melanoma stem cells (CSCs). whereas the assumption of melanoma stem cells has been round for greater than 100 years, facts from the fields of hematology and melanoma biology has now tested the serious position of stem cells in hematological malignancies and prompt that those comparable mechanisms also are relevant to the initiation, development, and remedy of good cancers. scientific and experimental reports have proven that CSCs express many classical homes of ordinary stem cells, together with a excessive self-renewal potential and the facility to generate heterogeneous lineages; the requirement for a selected “niche”/microenvironment to develop; and an elevated capability for self-protection opposed to harsh environments, pollution, and medication.
Cancer Stem Cells in sturdy Tumors represents a close assessment of melanoma stem cells and their function in stable cancers. constituted of 24 chapters, this quantity will offer readers with a finished realizing of this crucial and evolving field.
Topics lined include:
- Introduction of the CSC hypothesis
- Historical views and the contributing classes from leukemia
- Current wisdom in regards to the id and position of CSCs in a number of types of sturdy melanoma together with breast, mind, colorectal, pancreatic, prostate, cancer, lung, ovarian, hepatocellular, and head and neck melanoma
- Molecular pathways inquisitive about using CSC functionality, with a specific specialize in the radical convergence of embryonic and tumorigenic signaling pathways
- In vitro and in vivo assays, version platforms, and imaging modalities for learning CSCs
- The medical value of CSCs for melanoma administration and therapy, together with very important implications for analysis, prediction, and remedy resistance
- Consideration of the debate surrounding the CSC speculation and significant unanswered questions during this field
This collective paintings was once written via a gaggle of renowned overseas specialists in melanoma biology, oncology, and/or stem cellphone biology. it is going to function a necessary source for tested researchers, professors, future health care execs, and scholars within the clinical and medical group who're investigating stem cells and/or oncology.
By J. Michael Bishop, Harold E. Varmus (auth.), Frederick F. Becker (eds.)
The impression of easy learn on oncology has been fairly awesome within the contemporary look for the reason for malignancy. both extraordinary is our appreciation of the reason for tumors in accordance with statement. Even within the earliest period of the examine of infectious ailments, it used to be proposed that tumorous development in animals and birds resulted from "minute" infectious debris. Experiments then supported the speculation, that the etiologic agent in lots of animal tumors used to be viral. the advance of molecular biology, supported via technical advances and conceptual realizing of macromolecular motion, resulted in an explosive elevate in reviews of animal oncogenic viruses. For a decade, new findings emerged from study laboratories revealing the large number of such brokers, the complicated ity in their interactions with cells, and the tantalizingly attainable mechanisms through which they may reason malignant transformation of the cellphone. time and again, clues emerged which advised the intervention of viral brokers in human tumors. A breathless pleasure pervaded either the medical and public groups as hugely publicized findings quickly each other. the thrill used to be no much less medical than it used to be functional, for implicit within the idea of the viral oncogen is the opportunity of particular virostatic or virotoxic brokers or of immunization.