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Additional info for ASME Bio Process Equipment (BPE) 2005
Preferred (minimum) piping/tubing slopes are as follows: (a) Short Runs, Field Installed. /ft (21 mm/m or approximately 2%) (b) Long Runs, Field Installed. 1 ⁄8 in. 5%) (c) Skidded Runs. /ft (21 mm/m or approximately 2%) (d) Transfer Panels. 1⁄4 in. 5%). 16 The system shall be designed to eliminate air pockets, and prevent or minimize air entrainment. 5 times the nominal tube diameter to prevent the deterioration of interior surfaces, (wrinkling, striations, and potential cracking). ) are used.
In temporary runs, 20 Copyright ASME International Provided by IHS under license with ASME No reproduction or networking permitted without license from IHS Licensee=spirax sarco ltd/5945840001 Not for Resale, 05/24/2006 01:53:20 MDT BIOPROCESSING EQUIPMENT ASME BPE-2005 compatible with cleaning or sterilizing conditions. 3 End Connections (a) End connections shall be of a material and design sufficiently rigid to withstand the combined forces of the burst pressure rating of the flexible element, the compression forces required to affect the secure assembly with the flexible element.
Clean gas or clean steam Min. Heat exchanger (double tubesheet) Compendial water distribution loop TE Min. Drain/ steam trap/ sample point Point-of-use/ sample valve Hose assembly Physical break Process equipment Drain (c) Integral Heat Exchanger (e) Hose Fig. 1 General. The CIP skid and system is one of the most important pieces of equipment when considering cleanability and cross-contamination. Functional components of the CIP such as filters, pumps, vessels, tubing, and piping shall be designed to be self-cleaning and abide by the guidelines of this Part.